Surgery confirms Pope Leo has lung cancer, part of right lung’s lower lobe removed

Hospital says operation a success, with prognosis expected to be 'excellent' since nodule was removed at early stage; recovery may allow pontiff to make South America trip

Pope Leo XIV arrives at the Agostino Gemelli Polyclinic in Rome, October 13, 2026, where he was expected to be operated on to remove a lung nodule. (AP Photo/Alessandra Tarantino)

ROME, Italy (AP) — Pope Leo XIV underwent surgery that confirmed that he has lung cancer, and doctors removed the lower lobe of his right lung, the Vatican said Tuesday.

The tests confirmed a diagnosis of lung adenocarcinoma, the Vatican said in a medical bulletin after the surgery on Tuesday. It said the diagnosis had been suspected by preoperative tests and was confirmed during surgery.

The 71-year-old was in the operating room for about 3 hours, the statement said. The surgery itself lasted approximately 90 minutes. “The surgery was successful, and there were no complications,” the statement added.

Leo had walked into Rome’s Gemelli hospital through the main entrance earlier in the day and waved to dozens of well-wishers who had gathered to greet him. The Vatican said the surgery would be performed by a team led by Gemelli’s chief thoracic surgeon, Dr. Stefano Margaritora.

The American pontiff has offered a rare level of transparency about the first publicly disclosed major health problem of his 17-month papacy. He revealed the discovery of the small, localized nodule during his Sunday noon prayer and announced that he would have it removed.

Oncologists said prior to the operation that even if the nodule turned out to be cancerous, Leo’s prognosis is “excellent” since it will have been removed at an early stage.

Medical Director Andrea Cambieri, right, greets Pope Leo XIV as he arrives at the Agostino Gemelli Polyclinic in Rome on October 13, 2026, where doctors expect to operate to remove a lung nodule. (AP Photo/Gregorio Borgia)

The Vatican on Monday canceled all of Leo’s audiences through October 20.

While Gemelli has a specific papal apartment that past popes have used, complete with a private chapel on the 10th floor, Leo will actually be staying in a nearby room since the papal apartment is currently undergoing renovations, according to the Vatican press office.

Recovery could allow November travel to South America

IEO advises patients not to fly for three weeks after surgery — which would give the pope just the interval needed to make his planned November 6-17 trip to Uruguay, Argentina and Peru, depending on his recovery. The current itinerary for the trip is ambitious and the longest of his papacy to date, calling for Leo to clock just over 31,000 kilometers (19,000 miles) on a dozen flights and two helicopter rides, and a significant altitude change in Peru.

“He has decided to undergo surgery soon in order to not change his plans for future overseas trips, so there is no need to worry, as it is not an emergency,” said Tokyo Cardinal Kikuchi Tsutomu, who saw Leo on Monday.

Pope was hospitalized for typhoid fever in 1985

This is believed to be the second hospitalization for Leo, who is known to be sporty and in good shape, with weekly tennis games and swimming.

As a young missionary priest, he came down with typhoid fever in 1985, soon after arriving in Chulucanas, Peru. The illness and hospitalization were a cathartic moment for him to decide to stay in the poverty and discomfort of Peru after living in relative comfort in Rome — a decision that ultimately paved the way to his papacy, according to an interview Leo gave to Elise Ann Allen in 2025 for “Pope Leo XIV: The Biography.”

According to the book, Leo said he prayed to God to let him die rather than suffer the “horrible” pain of the fever. “I was hooked up to an IV, and I said, ‘If this is your sense of humor, Lord, I think you could do a little better.’

“Obviously, I survived; I recovered, but it turned out to be a very significant moment for me, because it was like, ‘Well, you’ve already dealt with the illness; you already see what the needs are here — the order, the Augustinians, the church are telling you, ‘We need you here; go for it.’ I never looked back.”

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