Police say Route 1, the site of one of the explosions this morning, has reopened to traffic.
The highway serves as the main artery into Jerusalem.
Police warn that traffic will be heavy in the area.
Two explosions at two bus stops near entrances to Jerusalem killed one person and injured 22, police and medics said.
Police said the blasts were a terror bombing attack.
The first explosion occurred close to the main entrance of Jerusalem in Givat Shaul, shortly after 7 a.m., peak commuter hour.
A second blast occurred shortly after 7:30 a.m., at Ramot junction, another entrance to Jerusalem.
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