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Top 8 Best NMN Supplements Reviewed: Most Effective 2024 Brands Ranke

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Nicotinamide mononucleotide (NMN) supplements are more popular today than ever before.

NMN is a natural molecule linked to DNA repair, energy, metabolism, and anti-aging effects. Studies show taking NMN supplements could promote positive effects throughout the body.

All good NMN supplements claim to offer a strong dose of NMN with proven anti-aging effects. However, not all NMN supplements live up to the hype.

We tested today’s top NMN supplements to see what works – and what doesn’t. Here’s our ranking of the world’s best nicotinamide mononucleotide (NMN) supplements.

Our Rankings

Some NMN supplements are better than others. Some contain strong doses of pure NMN mixed with ingredients to maximize bioavailability. Other supplements contain proprietary formulas with weak doses of unlisted ingredients.

We tested, tasted, ranked, and rated today’s most popular NMN supplements. After hundreds of hours of research and debate among our editorial team, here’s how we ranked the world’s best nicotinamide mononucleotide supplements.

Liposomal NMN+

Liposomal NMN+ by GenF20 is the world’s best nicotinamide mononucleotide supplement. By taking two capsules of Liposomal NMM+ daily, you can promote cellular regeneration, mitochondrial function, and DNA health using proven ingredients.

In fact, according to GenF20, the formula starts to work in just two weeks, providing you with noticeable anti-aging effects soon after you start taking it – no matter your age. By continuing to take Liposomal NMN+, you can purportedly “start feeling decades younger now,” according to GenF20.

Each serving of Liposomal NMN+ contains a single active ingredient: 250mg of nicotinamide mononucleotide (NMN). To maximize absorption, GenF20 has blended the ingredients with a vegetable cellulose capsule and a phospholipid complex. These fats help protect the active ingredients from being broken down until they reach your digestive tract, which means you get the maximum possible amount of NMN.

250mg of NMN is the same dose used in clinical trials. And, with additional ingredients for absorption and bioavailability, Liposomal NMM+ is the top-ranked NMN supplement on our list.

Price: $69.95

Wonderfeel NMN

Wonderfeel NM is marketed as “the greatest upgrade for the human OS.” With Wonderfeel NMN, you can boost NAD levels using a patented type of NMN called Youngr NMN, helping you change the way you age.

Each two capsule serving contains 900mg of NMN, which is one of the strongest doses on our list. It’s a higher dose than what we see in many clinical trials, and it suggests Wonderfeel NMN could work as advertised to support powerful anti-aging effects throughout the body.

Wonderfeel NMN was developed by a biomedical scientist and Harvard-trained medical doctor named Dr. Andrew Salzman. Dr. Salzman holds over 50 patents and has 30+ years of NAD research experience. In fact, Dr. Salzman’s development of the original clinical stage PARP-1 inhibitor led to the world’s first treatment for increasing NAD levels.

According to Wonderfeel, the formula can improve focus and clarity, increase athletic performance, and recapture your youthful energy, among other benefits. Just take two capsules per day to get started.

Price: $88

Tru Niagen

Tru Niagen aims to be a superior NAD booster, delivering 300mg of NMN in each capsule. You take just one capsule per day to get an equivalent dose of NMN to what’s found in other supplements on our list. Tru Niagen is also available in stick packs.

According to the official Tru Niagen website, the supplement can increase blood NAD levels “by up to 51% in as little as two weeks,” helping to support anti-aging effects throughout the body. The formula is also one of the best-known NMN supplements in the industry, backed by two Nobel Prize winners, 40+ patents, and dozens of studies.

One of the biggest differences between Tru Niagen and other supplements on our list is that it doesn’t actually contain NMN: it contains nicotinamide riboside (NR), another precursor to NMN and NAD.

Some of the benefits of Tru Niagen include healthy aging and support for your brain, heart, muscles, immune system, cells, and stress management systems, among others. If you want to look and feel younger within two weeks, then Tru Niagen and its strong dose of NMN could help.

Price: $47


If you want the highest quality NMN supplements and are willing to pay, then Elysium’s lineup could be the right choice for you. The company maintains institutional partnerships with Oxford and Yale, and supplements have received NSF Certified for Sport certification, which means they meet some of the highest standards for purity and quality.

Elysium also invests in clinical trials, and the company’s products have completed or are going through 13 human clinical trials.

Today, Elysium offers a range of anti-aging formulas targeting different health and wellness goals – from healthy brain aging to better cellular energy. The company’s anti-aging formulas include:

  • Basis
  • Signal
  • Matter
  • Format
  • Index
    Elysium Basis contains 250mg of nicotinamide riboside (NR) in each two capsule serving. Nicotinamide riboside is another precursor to NMN and NAD, and some studies suggest it’s more effective for NAD than traditional NMN supplements. Elysium also mixes the active ingredient with pterostilbene (PT) to support advertised effects.

Price: $69

Life Extension NAD+ Cell Regenerator

Life Extension’s NAD+ Cell Regenerator helps to defend your body against cellular aging using nicotinamide riboside (NR). In fact, the supplement uses the same NR as Tru Niagen, with each serving containing 300mg of Niagen nicotinamide riboside to boost the production of NAD.

As one of the most affordable NMN supplements on our list, Life Extension NAD+ Cell Regenerator costs just $40.50 for a 30 day supply (30 capsules x 300mg of NR per capsule). By taking one capsule daily, you can purportedly support youthful levels of NAD, promote healthy cellular metabolism and energy production, and help fight fatigue and promote longevity, among other benefits.

Life Extension was founded with the goal of selling science-backed supplements for a healthier life. in addition to NAD+ Cell Regenerator, the company sells ashwagandha, multivitamins, brain health supplements, digestive health aids, and more.

Price: $69

Cymbiotika NMN

Cymbiotika NMN is a premium NMN supplement featuring a blend of nicotinamide mononucleotide (NMN) with trans-resveratrol. The formula works by neutralizing the harmful effects of free radicals, maintaining healthy DNA, reducing oxidative stress, and slowing premature aging, among other benefits.

Like other NMN supplements on our list, Cymbiotika NMN works as an NAD precursor. The supplement gives your body the building blocks it needs to create NAD, contributing to anti-aging effects throughout the body.

Cymbiotika NMN is also one of the few supplements on our list with active complementary ingredients. Each two capsule serving of Cymbiotika NMM contains 400mg of NMN along with 200mg of apigenin, 200mg of green tea extract, 100mg of resveratrol, and 100mg of green coffee bean extract. These complementary ingredients could contribute to anti-aging effects of their own while helping with inflammation and physical and cognitive effects of aging.

Overall, Cymbiotika is known for its premium supplements, and Cymbiotika NMN is one of the best NMN supplements you can buy today.

Price: $77

Alive By Nature Sublingual NMN

Alive by Nature offers a unique NMN supplement in the form of a sublingual powder. You place the powder underneath your tongue, then let it absorb over 30 seconds before swallowing the rest.

Today, Alive by Nature’s Sublingual Powder Pure NMN is one of only two NMN supplements on our list not found in a capsule. It’s found in a bioavailable powder to boost absorption. Instead of waiting for your body to break down the capsule or absorb the active ingredients, you can start absorbing them immediately. Each serving of the powder contains 125mg of NMN, although you can take a higher dose for better absorption.

One thing that drops Alive by Nature’s Sublingual Powder Pure NMN further down our list is the controversy surrounding the formula: in 2020, the FDA issued a warning letter to the Florida-based supplement company after the company promoted their sublingual powder as a potential remedy for COVID-19. The FDA warned Alive By Nature to take immediate against to remove these claims.

As a result of this controversy, Alive by Nature Sublingual Powder Pure NMN can be difficult to find online today. Nevertheless, it’s one of the most bioavailable, top-rated NMN supplements on our list.

Price: $59

Liftmode NMN

Liftmode NMN is a popular and well-rated NMN supplement that comes in the form of a powder – similar to Alive by Nature’s Sublingual NMN powder above.

Priced at just $26.68 for 5g of powder, Liftmode NMN is one of the best-value NMN supplements on our list. You get a strong dose of NMN, a precursor to NAD, to support powerful anti-aging benefits.

Liftmode aims to differentiate itself from competitors with micro-batch production and vacuum-sealed, iced shipping containers. Plus, the purity of Liftmode NMN – and all other Liftmode supplements – is verified by an independent third party.

Liftmode sells its NMN powder in 5g ($26.68), 10g ($46.68), or 1,000g ($3,186.68) options. Whether you want to make your own NMN supplements or take the powder directly, you have a variety of options with Liftmode’s bulk NMN formula.

Price: $26.68

How We Ranked

What separates the best NMN supplements from the good NMN supplements? What’s the difference between the top-ranked NMN supplements on our list and the ones that didn’t make the cut?

Our editorial team considered dozens of ranking factors to create our list. Here are some of the most important factors we considered when analyzing today’s top NMN supplements:

98% Pure NMN or Better: The best NMN supplements contain pure NMN at a concentration of 98% or higher. This concentration is shown to provide the most active effects. Some low-quality supplements appear to contain the right dose of NMN – but they use the wrong concentration, which means you don’t enjoy the active effects. The top-ranked NMN supplement on our list, GenF20’s Liposomal NMN+, uses 98% NMN – and the company provides a certificate of analysis to prove this purity.

Liposomes, Fatty Acids, or Other Ingredients for Absorption: NMN has been studied extensively for its effects, and studies have verified it works as advertised to support anti-aging. However, studies also show your body struggles to absorb NMN on its own. That’s why the best manufacturers wrap NMN in a liposome, a fatty acid layer, or a similar protective mechanism. This helps protect the NMN from being destroyed by your stomach acid before it reaches your gut. It’s like you have a “taxi” transporting the NMN exactly where it needs to go.

Strong Dose of NMN (Ideally, 250mg or Better): Most NMN studies use a dose of 250mg. That’s why we preferred NMN supplements with a similar dose. Studies show this dose can contribute to anti-aging effects and other positive effects throughout the body. We preferred supplements with a minimum dose of 250mg of NMN per serving.

Transparent Manufacturing Location & Information: We weren’t biased against specific manufacturing locations, but we did like supplements that disclosed manufacturing information upfront. We like to see where a supplement is made and the type of facility in which it’s made. Ideally, the NMN supplement is made in an FDA or BRC-registered facility (or the local equivalent) in conditions that meet or exceed good manufacturing practices (GMP) standards.

Certificates of Analysis: Some supplement companies claim to contain pure NMN at the right dose, but they don’t back up these claims with a certificate of analysis. The best NMN companies disclose the results of lab testing, making it easy to see exactly what’s inside the formula as verified by formal test results. GenF20, as mentioned above, provides a certificate of analysis to verify its supplement contains 250mg of NMN at a 98% purity per serving.

Moneyback Guarantee: NMN supplements may not work for everyone – even if you’ve done everything wrong. That’s why we like supplement companies that offer a moneyback guarantee. If you’re unsatisfied with your NMN supplement purchase for any reason, then you should be able to get a refund. The best companies offer refund policies of 60 days or longer, giving you ample time to try the supplement to see if it works.

Complementary Ingredients: We primarily judged each NMN supplement on its dose and purity of NMN. However, we also considered complementary anti-aging ingredients within the formula – like vitamins, minerals, herbs, or plants that could complement the effects of NMN. Cymbiotika NMN, for example, contains 400mg of NMN per serving along with resveratrol, green tea extract, and other active ingredients.

Pricing & Competitiveness: NMN supplements are surging in popularity. They’re more popular today than ever before. Many manufacturers take advantage of this popularity by doubling or tripling the price of their supplements. Whether you’re spending $200 or $20 on an NMN supplement, you should get good value. We considered the overall value and pricing competitiveness of the top NMN supplements on our list.

Manufacturer Reputation & Track Record: Some manufacturers have been creating high-quality nutritional supplements for decades. Others are new and unproven. Some have received warnings from the FDA, while others have a proven reputation for quality and consistency. We preferred manufacturers with a strong track record and good overall reputation.

Transparent Labeling & Ingredient Information: Some NMN supplement companies hide weak dosages within proprietary formulas, making it difficult to compare the supplement to other formulas. Other NMN supplement companies have transparent, fully-disclosed ingredients. When manufacturers hide ingredients or doses, it makes us wary about the NMN supplement.

Formulated by Doctors, Researchers, or Medical Experts: Some NMN supplements on our list were created by genuine medical doctors. Wonderfeel’s Youngr NMN, for example, was created by Dr. Andrew Salzman, a pioneer in the NAD supplement company. Other supplements received contributions from medical researchers and other professionals. The more medical experience there is behind a supplement, the more we like it.

Delivery Method & Overall Convenience: It’s easy to take one or two capsules of an NMN supplement daily with a glass of water. It may be slightly harder to take a sublingual powder, as it takes longer to hold the powder under your tongue. OVerall, most NMN supplements are easy to take, but we considered overall convenience and ease of use in our rankings.

Honest Advertised Effects: NMN won’t make you look 20 years younger overnight, nor will it help you lose 30lbs in a month without dieting or exercising. Some manufacturers advertise ridiculous, unrealistic benefits with their NMN supplements. We preferred manufacturers that were open and honest about the expected effects of their formulas.

How Does NMN Work?

NMN works as a precursor to NAD+. NAD+ has proven anti-aging effects, and some people take NAD+ supplements to support anti-aging effects.

However, studies show you can’t simply take NAD+ to reverse the effects of aging. Instead, you’re better off taking a precursor to NAD+ like NMN.

Most NAD in the body is derived from vitamin B3 – typically in the form of nicotinamide. NMN may sound like an exotic ingredient, but it’s just a form of vitamin B3 designed specifically to boost NAD levels.

Here’s the basics to how NMN works:

Nicotinamide mononucleotide (NMN) is a precursor to nicotinamide adenine dinucleotide (NAD+), a popular anti-aging molecule backed by decades of scientific research.

Studies show NAD+ has the potential to extend your lifespan and reverse many cognitive and physical effects of aging. In one groundbreaking study, for example, NAD+ extended lifespan in mice by 30%.

Unfortunately, NAD+ levels decline with age. By the time you’re in your 40s, NAD+ levels are half what they were when you were younger.

NAD+ is one of the most abundant molecules in the human body. It’s found in virtually every cell. It also helps regulate over 400 biological functions and helps to keep your 37.2 trillion cells alive and healthy.

You could take an NAD+ supplement to raise NAD+ levels in the body. However, studies show these supplements don’t work very well because NAD is unstable; instead, you’re better off taking a precursor to NAD+ like NMN.

When you take an NMN supplement, you’re giving your body the building blocks it needs to create NAD+ on its own, helping to boost NAD+ levels naturally.

There are other ways to boost NAD+ levels – like intermittent fasting and high intensity interval training. Some use NMN supplements to complement these strategies, while others use NMN supplements on their own to boost NAD+ levels.

As NMN supplement company GenF20 explains, “NMN can boost your NAD+ back to your youthful levels,” replenishing levels of the critical anti-aging molecule to help you achieve targeted anti-aging effects.

Benefits of NMN

People take NMN for a variety of reasons. Some simply want to look and feel younger overall. Others want to boost metabolism, lose weight, or improve heart health, among other areas.

Here are some of the benefits of NMN, according to NMN supplement companies and scientific research:

  • Boost daily energy
  • Support heart health
  • Improve sleep
  • Promote DNA repair
  • Increase metabolism
  • Power up mitochondria
  • Feel younger, stronger, and more alert
  • Potentially extend lifespan
  • Support stronger joints
  • Increase muscle strength
  • Support healthy blood pressure
  • Support sleep
  • Enjoy lightning-quick memory recall
  • Boost sex drive
  • Alleviate joint pain and support mobility
  • Strengthen the immune system
  • Improve mood
    Whether interested in the cognitive, physical, or mood-boosting effects of NMN, there are a variety of effects linked to the popular supplement.

Why Doesn’t NMN Work for Everyone?

Some people have taken NMN supplements and been disappointed by the results.

It’s easy to blame NMN itself for this lack of effectiveness. In reality, however, you should blame the supplement company.

There are three main reasons why some NMN supplements are less effective than others, including:

Reason #1: Fake NMN Supplements: Some NMN supplements are simply fake. They claim to contain NMN, but they actually contain a blend of B vitamins or herbs to trick you into thinking the supplement is working. You may be taking these NMN supplements daily thinking they’re legit, only to be taking a glorified multivitamin.

Reason #2: Poor Absorption: It’s difficult for your body to absorb NMN on its own. If you simply take a dose of powdered NMN, your body will destroy or lose most of the active ingredient before it reaches your digestive tract. Many of the top-ranked supplement companies listed above have avoided this issue using liposomes or fatty molecules. By wrapping the active ingredients in a layer of fatty acids, you can ensure the maximum possible amount of NMN gets absorbed.

Reason #3: Incorrect Dosages: Some NMN supplements only contain trace amounts of the active ingredients – like 50mg of NMN or less. Generally, top-ranked NMN supplements contain 100mg to 250mg of NMN per serving – or even more.

Reason #4: Incorrect Purity: The best NMN supplements use NMN with 98% purity or higher. This NMN is shown to support active effects. It’s also the same NMN used in clinical trials and studies. Some NMN supplements appear to contain the right dose of NMN, but they use a lower purity, weakening the overall effectiveness of the supplement.

Because of these four reasons, many are disappointed by NMN. However, it’s not NMN’s fault: it’s the supplement’s fault.

By choosing the top-ranked NMN supplements on our list above, you can maximize your chances of experiencing positive benefits from NMN.

Scientific Evidence for NMN Supplements

Growing evidence is supporting the benefits of NMN supplements, proving they could work as advertised to promote powerful anti-aging effects. Some studies have connected NMN supplementation specifically to heart health, brain health, or other aspects of health and wellness. We’ll review some of the science behind NMN below.

Cellular Energy: Some people take NMN supplements specifically to boost cellular energy, helping to rejuvenate physical and cognitive energy overall. Each cell in the body produces energy via its mitochondria. By targeting energy at the cellular level and promoting mitochondria, NMN supplements could help achieve powerful effects on overall energy. In a 2016 study, researchers found NMN helped with mitochondrial dysfunction associated with age, for example. As you get older, your mitochondria may not function as optimally as they used to function.

Improved Physical Energy & Performance: By supporting mitochondria and cellular energy, NMN supplements could boost physical energy, endurance, and performance. In a 2017 study, researchers found NMN functioned as an NAD precursor to protect against physical damage and boost physical endurance. A separate study found NMN improved physical stamina and endurance in old mice by up to 80%.

Cardiovascular Health: Heart disease is the number one killer worldwide. More people die of heart disease than any other specific condition. That’s why some take NMN to support cardiovascular health. According to a 2016 study, NMN supplementation could reverse vascular dysfunction and oxidative stress in aging mice. Oxidative stress (inflammation) is associated with worse cardiovascular health and overall poor blood flow. By supporting your body’s natural defense against inflammation, NMN could promote cardiovascular health and function.

Immune Support: Some studies have shown NMN supplementation can improve immune function. When your immune system is more efficient, your body is better able to fight disease and illness. According to a 2022 study, NMN supplementation can trigger “macrophages reprogramming,” helping your immune system function in a more optimal way. This effect was shown to reduce inflammation. If your immune system is overactive, you might have too much inflammation, making it harder for your body to fight off legitimate illnesses and infections.

Brain Health: Some take NMN to feel younger and support brain health, and multiple studies have validated the cognitive effects of NMN. According to a 2014 study, NMN improves energy activity and survival rate in cells with Parkinson’s disease, suggesting NMN could help defend against degenerative brain conditions. A separate study from 2019 found NMN improved blood flow and boosted cognitive function in a group of older mice, suggesting NMN has additional effects on brain health and cognitive performance. In fact, the study showed old mice performed as well as young mice on cognitive tests after taking an NMN supplement compared to a placebo.

Metabolism & Weight Loss: As you get older, your metabolism tends to decrease. NMN supplementation could boost metabolism, making it easier to lose weight. The faster your metabolism is, the more calories you burn on a daily basis, giving you a powerful weight loss advantage. A 2016 study found NMN mitigated age-associated physiological decline in mice, helping to boost metabolism regardless of age. Another study found NMN helped to boost weight loss results over a 6-week period in a group of obese female mice, with mice in the NMN group losing more weigh than mice in a placebo group.

DNA Repair: Some people take NMN daily for general “DNA repair.” Although it sounds like a vague, poorly explained benefit, DNA repair could help support overall health and wellness. Studies show your body struggles to repair its DNA when you have insufficient levels of NAD. When your DNA cannot repair itself, you’re more likely to experience the effects of aging. Studies show taking an NMN supplement could increase your body’s ability to repair its DNA.

Vision & Eyesight: Surprisingly, some studies have connected NMN to better eyesight and vision. By taking NMN daily, you could prevent the degeneration of photoreceptors, helping to restore vision. Some also take NMN to help with dry eye syndrome, as it could increase tear production.

Help with Inflammation: High levels of inflammation are associated with an increased risk of disease and illness. In fact, inflammation is the root cause of many diseases and illnesses. Many people take NMN daily to support their body’s natural defense against inflammation. NMN could help your body neutralize free radicals linked to inflammation, for example.

Blood Sugar & Insulin: Some studies have connected NMN to blood sugar control and insulin production. A 2020 meta-analysis, for example, found NMN supplementation “enhanced insulin secretion and insulin action,” which could help support healthy blood sugar levels.

Musculoskeletal Structure: People with low levels of NAD tend to have worse musculoskeletal structure than people with high levels of NAD, based on skeletal muscle biopsies from young and older adults. However, researchers found active older adults had similar NAD levels to younger adults, suggesting exercise and diet can help support NAD levels in various ways. Physical activity – particularly short interval training exercises like HIIT – can promote NAD levels throughout the body.

There are also plenty of general studies on NMN, its absorption into the body, and its overall effectiveness. That same 2020 meta-analysis linked above, for example, found NMN supplements are “rapidly absorbed and converted to NAD” within the body after consumption, making NMN a genuine precursor to NAD – and a proven way to raise levels of the critical anti-aging molecule within your body.

Similarly, a 2022 study found NMN was safe, with few reported side effects even when taking high doses for a long period of time. Across all NMN studies, researchers have reported few adverse effects whatsoever.

NMN Supplements Can No Longer Be Sold as Dietary Supplements in the United States

NMN supplements have been popular for around a decade, and many take NMN supplements daily for anti-aging effects and overall health and wellness.

However, NMN supplements may be too powerful: the FDA recently banned the sale of beta-nicotinamide mononucleotide (B-NMN) supplements because the ingredient is being investigated as a potential new drug, making it ineligible as a dietary supplement ingredient. Despite being safely sold as a dietary supplement for years, NMN supplements

The FDA announced the ruling in November 2022, with most retailers halting sales of NMN in early to mid-2023.

Prior to the ruling, the FDA had accepted NMN as a new dietary ingredient (NDI), allowing supplement companies to use and sell the ingredient. In October 2022, the FDA revoked the NDA, preventing companies from selling it in the United States.

NMN supplement companies are pushing back against the ruling, claiming NMN supplements are safe and proven to support various health and wellness goals. Today, you can continue to buy some NMN supplements online, and some see it as a “grey area.” Officially, however, NMN supplements are not eligible for general supplement sales as of late 2023.

FAQs About NMN Supplements

Our experts get plenty of questions about NMN supplements and how they work. Here are some of the answers to our most frequently asked questions:

Q: What is NAD?
Q: Nicotinamide adenine dinucleotide (NAD or NAD+) is a molecule produced by your body. Found in virtually every cell, NAD plays a critical role in DNA repair, energy, mitochondrial health, inflammation repair, and cellular signaling, among other crucial aspects of health and wellness.

Q: Why do people take NAD supplements?
A: NAD supplements are best-known for their anti-aging effects, and many older adults take NAD supplements daily to reverse physical and cognitive effects of aging. However, NAD supplements are popular at all ages to support physical recovery, inflammation, heart health, and more

Q: Why is NAD important?
A: As you age, NAD levels drop significantly. In fact, studies show people who are 15 have as little as 15% of the NAD levels they did at 25. These low NAD levels contribute to physical and cognitive symptoms of aging.

Q: What are NMN supplements?
A: NMN supplements work as precursors to NAD. They contain a dose of nicotinamide mononucleotide (NMN), a building block for NAD within the body. Studies show taking NMN supplements can boost NAD rapidly, giving your body the building blocks needed to create NAD and enjoy anti-aging effects.

Q: Are NMN supplements safe?
A: Research suggests NMN supplements are safe for most healthy adults to take. According to a 2022 study, NMN supplements were associated with no adverse effects even when taking large doses daily for 12 weeks. Most studies have not linked NMN supplementation to significant side effects. However, you should talk to your doctor before taking NMN supplements if you’re taking medication or have a medical condition.

Q: What’s the difference between NMN and NAD supplements?
A: NAD is a molecule naturally produced by the body. You could take raw NAD as a supplement. However, it’s unstable and not popular. Instead, many companies use NMN, a building block of NAD, to raise NAD levels within the body.

Q: What’s the difference between NMN and NR supplements?
A: NMN and NR supplements both deliver a building block of NAD, but they deliver different building blocks. NMN supplements contain nicotinamide mononucleotide, while NR supplements contain nicotinamide riboside (NR). These two ingredients have both been shown to raise NAD levels safely. However, they work in different ways, and some prefer one type of supplement or the other.

Q: Can I still order NMN supplements online?
A: The FDA banned the sale of NMN supplements in November 2022 because NMN is being actively studied as a pharmaceutical drug. Today, some retailers have restricted the sale of NMN supplements, while others allow you to easily order supplements online. Overall, NMN supplements are in a grey area, and the situation is changing. As of late 2023, you’re still able to purchase some NMN supplements online.

Q: What are the best food sources of NAD?
A: The best food sources of NAD include chicken, tuna, and turkey (which are rich with niacin, a building block of NAD), edamame (which contains natural NMN), and any foods rich in foods, phosphates, or enzymes linked to the production of NAD within the body.

Q: What do NMN supplements do?
A: NMN supplements support general anti-aging effects throughout the body. They can help with physical and cognitive aging, for example, making you look and feel younger. Some also use them for heart health, cognition, or other specific goals.

Q: How much NMN should I take? What’s the best dose?
A: Most NMN studies use a dose of around 250mg of NMN per day. However, studies show NMN is safe to take at 500mg to 1,000mg per day, and some NMN supplements contain as much as 900mg per serving.

Q: Who is Dr. David Sinclair?
A: Dr. David Sinclair is a Harvard University professor who has pioneered NMN and NAD research. He’s part of several groups investigating the anti-aging effects of NAD and NMN. Dr. Sinclair is particularly notable in the NMN supplement space because he recommends taking NMN supplements – not NR supplements – to raise NAD levels.

Q: What’s the best way to boost NAD levels?
A: You can boost NAD levels by taking an NMN or NR supplement. Alternatively, studies show a healthy diet and exercise routine can boost NAD levels. In fact, active older adults can have the same NAD levels as younger adults, and exercise appears to be particularly important for NAD levels.

Q: Does HIIT boost NAD?
A: Studies suggest rapid bursts of intense exercise – like high intensity interval training, or HIIT – can boost NAD levels.

Q: What’s the best NMN supplement?
A: According to our analysis, the best NMN supplement is Liposomal NMN+ from GenF20, followed closely by Wonderfeel NMN, Tru Niagen, Elysium NMN, and Life Extension NAD+ Cell Regenerator, among other formulas.

Q: Why are NMN supplements so expensive?
A: NMN supplements may be more expensive because of the high manufacturing costs. It costs a lot of money to produce 98% pure or higher NMN. And, because NMN supplements are trendy, supplement companies don’t feel the need to reduce their NMN supplement pricing.

Q: How do I take NMN?
A: Most NMN supplements come in the form of a convenient capsule. You take a capsule or tablet daily to promote NMN and NAD levels. Some NMN supplements come in the form of a powder.

Q: When is the best time to take NMN?
A: Most experts recommend taking NMN each morning on an empty stomach to maximize absorption and bioavailability.

Final Word

NMN supplements are more popular than ever before. They’ve been shown to raise NAD levels, helping you support your body’s natural defense against physical and cognitive aging.

Whether you’re an older adult who wants to feel young again or a younger adult looking to boost performance, you could experience a range of noticeable effects with NMN supplements.

To learn more about NMN supplements or to find the best NMN supplements available today, check our list of the best NMN supplements above.

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

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