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Best Weight Loss Pills in 2023: Top Diet Supplements Benefits, Price, Side Effects

Promoted Content: Looking for the best weight loss pills to help you shed those extra pounds? Discover the top-rated products based on effectiveness, safety, and customer reviews.

You want to lose weight for many reasons: to feel healthier, look better, or enjoy life more. But it’s not easy to resist the temptation of foods that make the journey a tough hill to climb.

A lot of people swear by natural weight loss pills, but are they effective and safe? Which ones are worth your money? Find out today.

We did the research and found some of the best weight loss pills on the market. Whether to suppress appetite, give you better gym results, or something cheap to get started, they’re all here.

Read on to find out why we recommend PhenQ as our #1 choice and other options you can try.

Top Weight Loss Pills of 2023: First Look

1. PhenQ – Best Weight Loss Pills Overall


  • 60-days money-back guarantee
  • No extra cost for shipping
  • Supports thermogenesis to burn more calories
  • Helps you control your hunger and cravings
  • All-natural ingredients


  • May cause jitteriness or insomnia for those who are sensitive to caffeine

Who Is PhenQ Best For?

PhenQ is one of the best weight loss pills overall that combines natural ingredients to target fat loss from different angles, including appetite suppression and much higher energy metabolism.

It contains a-Lacys Reset, a patented formula that helps you lose weight and maintain muscle mass [1]. It also has nopal powder, a cactus extract that can block fat absorption [2].


PhenQ is our top-rated choice for the best pills for weight loss that uses various ingredients to support fat loss and overall health. 

>>Check best prices for PhenQ

2. Keto Charge – Best for Keto Diet


  • Supports ketosis
  • Boosts energy and performance in physical and mental tasks
  • Helps curb appetite and increase fullness


  • May cause gut issues
  • Only sold online

Who Is Keto Charge Best For?

Keto Charge is designed for people who are on a keto diet and want to improve their weight loss results. This supplement helps you burn fat faster by enhancing ketosis, increasing energy, and reducing cravings for carbs and sugar [3].


The recommended dosage is two capsules per day, preferably with a meal. You can also adjust the dosage according to your individual needs and goals.


Keto Charge is a reliable weight loss supplement t

hat complements your keto diet. It supports ketosis, helps you lose weight, and controls your appetite.

>>Check best prices for Keto Charge

3. Phen24 – Best for Thermogenesis


  • Clinically tested ingredients for weight loss
  • Money-back guarantee for 60 days
  • Two-in-one formula for day and night support
  • Free delivery within the US


  • Only sold on the official website of the brand
  • Not available for worldwide shipping

Who Is Phen24 Best For?

Phen24 is a great option for anyone who wants to boost their metabolism and lose weight faster. It’s ideal for increasing thermogenesis, which can lead to burning more calories.


Phen24 is a unique weight loss supplement that works both day and night. It can help you control your appetite, burn more fat, and improve your mood and focus during the day. At night, it can help you sleep better and prevent late-night cravings.

>>Check best prices for Phen24

4. Instant Knockout – Best Weight Loss Pills for Lifters


  • High energy due to high caffeine content
  • Provides essential vitamins such as B6 and B12
  • Helps control hunger w
    ith glucomannan


  • Some ingredients may cause adverse effects in high doses

Who Is Instant Knockout Best For?

Instant Knockout is a top-rated weight loss pill for lifers. It contains ingredients like caffeine and B-vitamins that help give you a better gym experience by supporting high energy levels. With Instant Knockout, you can achieve your weight loss goals faster with each rep and set.


Instant Knockout is a weight lo


ss pill that can help you burn fat, suppress appetite, and boost energy. It is designed for active men who want to get in shape and improve their performance.

>>Check best prices for Instant Knockout

5. CalmLean – Best Stimulant-Free Weight Loss Pills


  • All-natural and caffeine-free ingredients
  • Proven to be safe and effective by clinical studies
  • No prescription needed to buy the formula
  • May enhance metabolism and fat burning


  • Only available on the official website

Who Is CalmLean Best For?


CalmLean is a great choice for anyone who wants to lose weight without any stimulants. This weight loss supplement is made of natural ingredients that won’t affect your sleep or energy levels. It’s suitable for those who are sensitive to caffeine or other stimulants.


CalmLean is a natural weight loss supplement that can help you lose weight safely and easily without stimulants. It can boost your metabolism and help you burn more fat without the jitters.

>>Check best prices for CalmLean

6. Brutal Force ACUT – Best Anavar Alternative


  • Natural and vegan-friendly ingredients
  • Increases your energy levels and thermogenesis
  • Curbs your hunger and cravings
  • 100-day money-back guarantee


  • Contains caffeine, which may cause jitteriness
  • May interact with some medications

Who Is Brutal Force ACUT Best For?

Brutal Force ACUT may be suitable for people who are looking for a natural and vegan-friendly alternative to Anavar. It may be especially beneficial for those who struggle with low energy levels, slow metabolism, or excessive appetite.


Brutal Force ACUT is a natural supp

lement that helps you burn fat and get a lean, muscular, and strong physique. It is formulated like Anavar, but has a lower risk of side effects.

>>Check best prices for Brutal Force ACUT

7. Brutal Force WINCUT – Best Winstrol Alternative


  • Natural fat burner that gives you similar results to Winstrol
  • Burn fat, harden muscles, and enhance vascularity
  • Natural ingredients that improve your energy, endurance, and speed
  • No injections required
  • Offers free worldwide shipping and bulk discounts


  • Requires 60 days of use for best results

Who Is Brutal Force WINCUT Best For?

Brutal Force WINCUT is for you if you want to get the benefits of Winstrol without the risks of using an illegal steroid. It is a natural alternative that can help you lose weight and get lean in a safer, legal way.



Brutal Force WINCUT is a natural supplement that mimics the effects of Winstrol, a potent steroid for cutting and performance. It helps you burn fat, build stronger muscles, and enhance blood flow without harming your health or breaking the law.

>>Check best prices for Brutal Force WINCUT

8. Zotrim – Best Appetite Suppre


  • Suitable for vegans
  • Helps control appetite
  • Made from natural, plant-based ingredients


  • Unclear refund policy
  • Up to 9 tablets per day

Who Is Zotrim Best For?

Zotrim is a great option if you want a natural weight loss supplement that reduces appetite. It claims to help you lose weight, manage your hunger, and enhance your well-being.



Zotrim is one of the best weight loss supplements you can find. It helps you avoid excessive eating and achieve lasting weight loss.

>>Check best prices for Zotrim

9. Powher – Best Weight Loss Pills for Women


  • Tailored for women’s needs
  • Made in an FDA-registered facility
  • Suppresses appetite and cravings
  • Enhances energy for workouts


  • No independent reviews

Who Is Powher Best For?

Powher Cut is a dietary supplement created for women who struggle to lose weight despite following diet and exercise plans. The supplement helps to address issues such as stubborn fat, low energy levels, and cravings.


Powher is one of the best weight loss pills that actually work for women. Individual results may vary depending on body composition and other factors, but the formula supports a healthy lifestyle with exercise, balanced diet, and rest.

>>Check best prices for Powher

10. Leanbean – Best Weight Loss Pills for Belly Fat


  • Contains B vitamins
  • Helps curb hunger with Glucomannan, a natural fiber
  • Enhances fat burning with Carnitine, an amino acid


  • Often sold out due to popular demand

Who Is Leanbean Best For?

Leanbean is specially formulated to target stubborn belly fat and boost metabolism. It contains natural ingredients that boost your metabolism and provide essential nutrients to improve workout performance.


Leanbean is a weight loss solution for belly fat. It comes with natural ingredients that stimulate thermogenesis and reduce appetite. It also has minimal caffeine content, so it may not lead to jitters or caffeine crashes.

>>Check the best prices for Leanbean

11. Trimtone – Most Convenient Weight Loss Pill


  • One capsule a day is all you need
  • Contains Glucomannan, a natural fiber that helps control appetite
  • Ideal for active women who want to lose weight
  • Has caffeine to enhance energy levels and metabolism


  • Only offers a 14-day money-back guarantee

Who Is Trimtone Best For?

Trimtone is a weight loss supplement that combines the appetite suppressing effect of glucomannan and the energy and metabolism support of caffeine. This supplement can help you achieve your fitness goals with just one pill a day.

It’s also heavily advertised for women who may dislike supplements that ask them to take too many pills per day.


Trimtone is a recommended choice for weight loss pills as it uses natural ingredients like glucomannan and caffeine to reduce appetite and increase metabolism. The supplement has low doses of ingredients, reducing the risk of side effects while still delivering effective results. Its main draw, however, is how it’s formulated to work with just one pill a day.

>>Check best prices for Trimtone

12. PrimeShred – Best Weight Loss Pills for Men


  • Supports overall metabolism
  • Helps control hunger with natural ingredients
  • Offers a 100-day money-back guarantee if not satisfied
  • Increases energy levels and mood


  • The money-back guarantee has some restrictions
  • Free shipping is only available for large orders

Who Is PrimeShred Best For?

PrimeShred is a weight loss supplement formulated for men who want to enhance their body’s ability to burn fat for energy, supporting overall metabolic efficiency.


PrimeShred is a top-rated weight loss pill that uses natural ingredients to enhance metabolism and fat burning. It also contains tyrosine and theanine, which can help you relax and focus [4].

>>Check best prices for PrimeShred

13. Transparent Labs – Best for Menopausal Women


  • Contains 5-HTP, theanine, and tyrosine, which may improve mood [5] [6]
  • Fights inflammation with natural ingredients
  • Boosts metabolism and energy levels with stimulants like caffeine


  • Does not offer free shipping for any order

Who Is Transparent Labs Best For?

Transparent Labs’ fat burner is a weight loss supplement designed for menopausal women because of its weight loss and mood support formula. This has ingredients like 5-HTP that can enhance mood and reduce stress. It also contains caffeine and synephrine, which can increase energy and metabolism.


Transparent Labs offers a weight loss supplement that uses natural ingredients like caffeine and cayenne pepper extract to burn fat . It also includes ingredients like 5-HTP and theanine that support the emotional and mental aspects of weight loss, especially in menopausal women.

>>Check best prices for Transparent Labs

What Are Weight Loss Supplements?

As the name implies, weight loss supplements are designed to help you lose weight by affecting your metabolism, appetite, or fat absorption. They often come in capsules, tablets, or softgels.

How Do Weight Loss Pills work?

  • Some of them can speed up your metabolism and make you burn more calories. They can boost your energy and help you shed pounds faster [7] [8].
  • Other weight loss supplements can make you feel full and help you eat less. They do this by making you feel full.
  • They can also work by blocking the absorption of fat from food. By reducing the calories and fat that you get from your diet, they can help you lose weight.

How We Selected the Best Weight Loss Pills of 2023

Choosing the best weight loss supplements can be challenging, as there are many factors to consider before making a purchase.

Here are some of the most important ones:

The Reputation of the Company

You want to buy from a company that has a good reputation in the industry, follows good manufacturing practices, has positive customer reviews and testimonials, and offers reliable customer service and support.

High-Quality Ingredients

Look for supplements that contain high-quality ingredients backed by scientific research and proven to be effective for weight loss. Avoid supplements that contain artificial colors, flavors, preservatives, fillers, or other unnecessary additives.

Side Effects and Safety

You should consult your doctor before taking any supplement, especially if you have any medical condition, are pregnant or breastfeeding, or are taking any medication. Choose weight loss supplements that are known for safety and do not cause any harmful or unpleasant side effects.

>>Check best prices for PhenQ


Compare the price, quantity, and quality of different supplements and look for discounts, coupons, or free trials if available. Consider the cost of shipping and handling and the return policy of the company.

Product Effectiveness

Go for brands designed to work for your specific needs and help you achieve your weight loss goals. Look for supplements with positive feedback from customers who share similar goals.

Daily Dosage

You want to choose supplements that are easy to use and do not require you to take too many pills or servings per day. Look for supplements that have a clear and simple dosage instruction on the label like Trimtone with just one capsule a day.

Money-Back Guarantee and Refund Policies

You want to choose supplements that come with a money-back guarantee or a refund policy in case you are not satisfied with the product or its results. Check the terms and conditions of the guarantee and understand how to claim your refund if needed.

>>Check best prices for PhenQ

How to Get the Best Results With Diet Pills

As cliche as it sounds, these diet pills work best when combined with a balanced diet, regular exercise, and other healthy lifestyle habits.

Here are some tips on how to get the best results with weight loss pills that actually work:

Balanced Diet

Aim for a diet rich in fruits, vegetables, whole grains, lean protein, and healthy fats. Avoid foods that are high in calories, sugar, salt, and saturated fat.

Drink Plenty of Water

Water helps you stay hydrated, flush out toxins, and prevent constipation. It also helps you feel full and reduce your appetite.

Regular Exercise

Weight loss pills that actually work can boost your metabolism and help you burn more calories, but they cannot replace physical activity. Exercise is important for your overall health, fitness, and mood. It also helps you build muscle, tone your body, and prevent weight regain.

Get Enough Sleep

Sleep is vital for your health and weight loss. It helps you regulate your hormones, repair your tissues, and recharge your energy. It also affects your appetite and cravings. Lack of sleep can make you hungry, irritable, and prone to overeating.

Stress Management

Stress can have a negative impact on your health and weight loss. It can trigger emotional eating, increase your cortisol (the stress hormone) levels, and slow down your metabolism. Consider finding other healthy ways to cope with stress.

>>Check best prices for PhenQ

Types of Weight Loss Pills

There are many types of weight loss pills that actually work on the market. Some of the most common types are:

Appetite Suppressants

If you find yourself having sudden hunger pangs, try appetite suppressants. These may help you eat less and lose weight by reducing your hunger and making you feel full sooner.

Thermogenic Fat Burners

The most popular type of weight loss supplement, thermogenic fat burners may stimulate your nervous system and increase your energy levels. They’re often formulated with stimulants like caffeine, so they may not be for everyone.

Carb Blockers

Carb blockers reduce enzymes that digest carbohydrates, which lowers the amount of calories and sugar that your body absorbs from starchy foods. They may also lower your blood sugar levels and prevent insulin spikes, which contribute to hunger.

Fat Blockers

In the same light as carb blockers, fat blockers lower enzyme activity involved in fat absorption, which reduces the amount of calories from fatty foods.

Metabolism Boosters

These weight loss pills that actually work enhance your body’s natural ability to burn calories and fat. They may also improve your thyroid function, which regulates your metabolism.

>>Check best prices for PhenQ

Prescription Weight Loss Pills

Prescription weight loss pills are medications formulated with synthetic ingredients to help you lose weight, especially if your doctor diagnoses you with obesity.

Some of the most common prescription weight loss pills are:

  • Orlistat (Alli, Xenical): This pill blocks the enzyme that breaks down fat in your digestive system, so you absorb less fat from your food.
  • Liraglutide (Saxenda): This is an injectable drug that mimics a hormone called GLP-1, which regulates your appetite and blood sugar.
  • Phentermine-topiramate (Qsymia): Phentermine suppresses your appetite, while topiramate reduces your cravings and makes you feel full.
  • Naltrexone-bupropion (Contrave): Naltrexone blocks the effects of opioids and reduces your reward response to food, while bupropion increases your mood and energy levels.

Common Ingredients in Best Weight Loss Pills

Here are some of the common ingredients found in weight loss pills that actually work and what they do:

Garcinia Cambogia Extract

Derived from a tropical fruit, it contains hydroxycitric acid (HCA), which is believed to suppress appetite and inhibit fat storage [9].

Raspberry Ketones

These compounds give raspberries their distinct aroma. They’re thought to affect metabolism and increase the breakdown of fat [10].

Green Coffee Bean Extract

It contains chlorogenic acid, which may help lower blood sugar levels and reduce fat absorption, leading to potential weight loss [11].


Derived from the root of the konjac plant, glucomannan is a dietary fiber that can absorb water and help you feel fuller, potentially reducing calorie intake [12].

Green Tea Extract

Rich in antioxidants and catechins, green tea extract is believed to boost metabolism and aid in fat burning [13].

Conjugated Linoleic Acid

It’s a type of fatty acid found in dairy and meat products, CLA is thought to reduce body fat and promote lean muscle mass [14].

>>Check best prices for PhenQ


Here, we answer a few frequently asked questions about the best weight loss pills.

Do Weight Loss Pills Have Any Side Effects?

Yes, and this depends on ingredients, dosage, and interactions with other medications. If side effects persist, stop taking weight loss pills and consult with your doctor.

Are Natural Weight Loss Pills FDA Approved?

No, weight loss pills are not FDA-approved. Natural weight loss pills are usually classified as dietary supplements, which do not require approval by the Food and Drug Administration (FDA) as drugs.

>>Check best prices for PhenQ

Are Natural Diet Pills Effective for Weight Management?

Yes, natural weight loss pills may be effective for weight management by influencing appetite, metabolism, fat absorption, or energy expenditure. However, some natural diet pills do not work for others due to individual differences in genetics, physiology, lifestyle, and preferences.

Can Weight Loss Supplements Work Without a Healthy Diet and Exercise?

If you continue to consume more calories than you burn, you will not lose weight or you will regain the weight you lost even with the best weight loss pills. The only way to achieve long-term and sustainable weight loss is to adopt a healthy lifestyle that includes a balanced diet and regular exercise.

Can Weight Loss Products Help Prevent Weight Gain and Obesity?

Weight loss pills can help you avoid weight gain and obesity by supporting a healthy body weight or burning excess calories. However, weight loss pills are not a magic solution for weight gain and obesity.

How Long Does It Take for Diet Supplements To Work?

Different diet supplements work at different speeds. Some may affect your appetite or energy right away. Others may take weeks or months to improve your metabolism or fat absorption.

Best Weight Loss Pills: Final Note

You deserve the best weight loss pills that suit your goals, preferences, and needs.

That’s why we reviewed the weight loss supplements that use natural and safe ingredients, have reasonable prices, and have real customer feedback to back up their claims. In our search, we found that PhenQ is the best weight loss pills overall.

What makes PhenQ superior is how it attacks fat in many ways, including supporting metabolism and appetite control.

But don’t expect any miracles from weight loss pills. You still need to put in some effort to eat healthy and exercise regularly. That’s the only way to get the best results.

>>Check best prices for PhenQ


  1. Kucukgoncu, S et al. “Alpha-lipoic acid (ALA) as a supplementation for weight loss: results from a meta-analysis of randomized controlled trials.” Obesity reviews : an official journal of the International Association for the Study of Obesity vol. 18,5 (2017): 594-601. doi:10.1111/obr.12528
  2. Onakpoya, Igho J., et al. “The Effect of Cactus Pear (Opuntia Ficus-Indica) on Body Weight and Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.” Nutrition, Elsevier, 19 Dec. 2014,
  3. Rho, Jong M, and Raman Sankar. “The Ketogenic Diet in a Pill: Is This Possible?” Epilepsia, U.S. National Library of Medicine, Nov. 2008,
  4. GN;, Nobre AC;Rao A;Owen. “L-Theanine, a Natural Constituent in Tea, and Its Effect on Mental State.” Asia Pacific Journal of Clinical Nutrition, U.S. National Library of Medicine, 2008,
  5. “Tyrosine.” Tyrosine – Health Encyclopedia – University of Rochester Medical Center,
  6. Maffei M. E. (2020). 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. International journal of molecular sciences, 22(1), 181.
  7. Belza, A, et al. “The Effect of Caffeine, Green Tea and Tyrosine on Thermogenesis and Energy Intake.” Nature News, Nature Publishing Group, 19 Sept. 2007,
  8. Leung, Felix W. “Capsaicin as an Anti-Obesity Drug.” SpringerLink, Springer Basel, 1 Jan. 1970,
  9. Ji-Eun Kim et al. “Does Glycine Max Leaves or Garcinia Cambogia Promote Weight-Loss or Lower Plasma Cholesterol in Overweight Individuals: A Randomized Control Trial.” Nutrition Journal, U.S. National Library of Medicine,
  10. Morimoto C;Satoh Y;Hara M;Inoue S;Tsujita T;Okuda H; “Anti-Obese Action of Raspberry Ketone.” Life Sciences, Accessed 10 Aug. 2023.
  11. Haidari, Fatemeh et al. “Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women.” Asia Pacific journal of clinical nutrition vol. 26,6 (2017): 1048-1054. doi:10.6133/apjcn.022017.03
  12. Kaats, Gilbert R et al. “Konjac Glucomannan Dietary Supplementation Causes Significant Fat Loss in Compliant Overweight Adults.” Journal of the American College of Nutrition, 1-7. 22 Oct. 2015, doi:10.1080/07315724.2015.1009194
  13. Hodgson B. Adrian et al. “The Effect of Green Tea Extract on Fat Oxidation at Rest and during Exercise: Evidence of Efficacy and Proposed Mechanisms.” Advances in Nutrition (Bethesda, Md.), American Society for Nutrition, 1 Mar. 2013,
  14. Lehnen, Tatiana Ederich, et al. “A Review on Effects of Conjugated Linoleic Fatty Acid (CLA) upon Body Composition and Energetic Metabolism.” Journal of the International Society of Sports Nutrition, 17 Sept. 2015,

Author Details


Author Email

Jamila Khan

Jamila Khan is a practicing doctor of dental medicine with a passion for creating content in several niches, particularly the health and wellness space. She specializes in consumer health, mental health, sleep health, health technology, and women’s health.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

This article is sponsored content. No endorsement by The Times of Israel of advertiser products or services, real or implied, is intended. The Times of Israel editorial team did not contribute to this article.