Prime Minister Benjamin Netanyahu will undergo a medical procedure Thursday evening, under sedation, leaving Jerusalem Affairs Minister Ze’ev Elkin (Likud) to serve as acting PM while he is incapacitated.

The Prime Minister’s Office said Thursday the procedure involves “the removal of a stone from the bladder.”

Netanyahu will be accompanied by his personal physician, Dr. Tzvi Berkovich, his office said. It was not immediately clear which hospital will host the procedure.

The procedure comes after a series of intense days for the prime minister in which he hosted US President Donald Trump on Monday and Tuesday and gave a series of speeches Wednesday as Israel marked the 50th anniversary of the reunification of Jerusalem in the 1967 Six Day War.

In December 2015, Netanyahu underwent an exploratory colonoscopy, also under sedation, leaving then-defense minister Moshe Ya’alon in charge.

The tests revealed a number of polyps, which were successfully removed, his office said at the time.

In 2013, the prime minister also underwent an emergency hernia operation, and a similar colonoscopy in 2014 as part of his annual health examination, whose results were released to the public.

Netanyahu is 67 years old. At his last annual check-up in August 2016, he received a clean bill of health. In the annual medical report for the prime minister, Berkovich reported the premier’s health to be “excellent,” and said that Netanyahu maintains a “healthy lifestyle and healthy eating habits.”