Iran’s Khamenei says nuclear talks with US unlikely to ‘lead to any outcome’

Ayatollah says American negotiators should ‘refrain from speaking nonsense’ after Witkoff says Tehran will not be allowed to enrich uranium

Supreme Leader Ayatollah Ali Khamenei speaks during a memorial in Tehran, Iran, May 20, 2025 for late president Ebrahim Raisi, who died in a helicopter crash last year. (Office of the Iranian Supreme Leader via AP)
Supreme Leader Ayatollah Ali Khamenei speaks during a memorial in Tehran, Iran, May 20, 2025 for late president Ebrahim Raisi, who died in a helicopter crash last year. (Office of the Iranian Supreme Leader via AP)

TEHRAN, Iran (AFP) — Iran’s supreme leader Ayatollah Ali Khamenei said Tuesday that nuclear talks with the United States were unlikely to yield any results, amid a diplomatic standoff over the Islamic Republic’s enrichment activities.

“We don’t think it will lead to any outcome. We don’t know what will happen,” said Khamenei during a speech, adding that denying Iran’s right to enrich uranium was “a big mistake.”

Iran and the United States have held four rounds of Omani-mediated nuclear talks since April 12, the highest-level contact between the two foes since Washington abandoned the 2015 nuclear accord.

They had confirmed plans to hold another round of discussions during their last meeting on May 11, which Iran described as “difficult but useful,” while a US official said Washington was “encouraged.”

Iran currently enriches uranium to 60 percent, far above the 3.67% limit set in the 2015 deal and a technical step away from the 90% needed for a nuclear warhead. Western countries, including the United States and Israel, have long accused Iran of seeking to acquire atomic weapons, while Iran insists its nuclear program is for peaceful purposes.

Iran has repeatedly insisted its right to maintain uranium enrichment was “nonnegotiable,” while chief US negotiator Steve Witkoff has called it a “red line.”

In this photo released by Iranian Foreign Ministry, Iranian Foreign Minister Abbas Araghchi, right, steps out from his plane as he arrives at Muscat, Oman, Friday, April 25, 2025, a day prior to negotiations with US Mideast envoy Steve Witkoff. (Iranian Foreign Ministry via AP)

On Sunday, Witkoff reiterated that the United States “cannot allow even one percent of an enrichment capability.”

Khamenei said Tuesday that “the American side involved in these indirect negotiations should refrain from speaking nonsense.”

Earlier, Iran’s Foreign Minister and lead negotiator Abbas Araghchi said “enrichment in Iran, however, will continue with or without a deal.”

“If the US is interested in ensuring that Iran will not have nuclear weapons, a deal is within reach, and we are ready for a serious conversation to achieve a solution that will forever ensure that outcome,” he wrote in a post on X.

This picture shows a replica of Iran’s Bushehr Nuclear Power Plant at an exhibition at the International Conference on Nuclear Science and Technology in Isfahan in on May 6, 2024 (Atta Kenare/AFP)

Iranian diplomats have said Tehran would be open to temporary restrictions on how much uranium it enriches and to what level.

Since returning to office in January, US President Donald Trump has revived his “maximum pressure” approach against Iran. While backing nuclear diplomacy, he also warned of potential military action if it fails.

Trump has said he presented Iran’s leadership with an “olive branch,” adding that it was an offer that would not last forever. He further threatened to impose “massive maximum pressure,” including driving Iranian oil exports to zero if talks failed.

Trump later doubled down on his warning, saying that “something bad is going to happen” unless the Iranians “move quickly” toward a deal.

US Special Envoy to the Middle East Steve Witkoff arrives for a signing ceremony at the Royal Palace in Doha on May 14, 2025. (Karim JAAFAR / AFP)

Iranian officials, however, criticized what they described as “contradictory” positions by US officials along with the continued imposition of sanctions targeting Iran’s oil industry and nuclear program despite the talks.

On Sunday, Araghchi said Iran has been observing “dissonance… between what our US interlocutors say in public and in private.”

On Friday, Iran held parallel talks with the Britain, France, and Germany — all parties to the 2015 deal. They are currently weighing the reimposition of UN sanctions in response to Iranian non-compliance. The option to trigger the sanctions mechanism expires in October.

Araghchi said Iran was willing to “begin a new chapter” with Europe and urged it to play a role in the nuclear negotiations.

Times of Israel staff contributed to this report.

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