Explainer

3 days, 640,000 children, 1.3M doses: The plan to vaccinate Gaza’s kids against polio

International agencies set to kick off inoculation drive using ‘humanitarian pauses’ on Sunday amid fears there could be hundreds infected with disease

A nurse administers Polio vaccine drops to a girl at the Nasser hospital in Khan Yunis in the southern Gaza Strip on August 31, 2024 (Jihad Al-Sharafi / AFP)
A nurse administers Polio vaccine drops to a girl at the Nasser hospital in Khan Yunis in the southern Gaza Strip on August 31, 2024 (Jihad Al-Sharafi / AFP)

The United Nations health agency and partners are launching a campaign starting Sunday to vaccinate 640,000 Palestinian children in Gaza against polio, an ambitious effort amid a devastating war that has destroyed the territory’s healthcare system.

The campaign comes after the first polio case was reported in Gaza in 25 years — a 10-month-old boy, now paralyzed in the leg.

The World Health Organization says the presence of a paralysis case indicates there could be hundreds more who have been infected but aren’t showing symptoms.

Most people who have polio do not experience symptoms, and those who do usually recover in a week or so.

But there is no cure, and when polio causes paralysis it is usually permanent. If the paralysis affects breathing muscles, the disease can be fatal.

The vaccination effort will not be easy: Gaza’s roads are largely destroyed, its hospitals badly damaged and its population spread into isolated pockets.

Palestinian boy Abdel Rahman Abu al-Jedian who contracted polio a month ago, sleeps surrounded by family members in their displacement tent in Deir al-Balah in the central Gaza Strip on August 27, 2024. (Eyad Baba/AFP)

WHO said Thursday that it had reached an agreement with Israel for limited pauses in the fighting to allow for the vaccination campaign to take place.

Even so, such a large-scale campaign will pose major difficulties in a territory blanketed in rubble, where 90 percent of Palestinians have been displaced since the start of the war triggered by Hamas’s devastating October 7 attack.

How long will it take?

The three-day vaccination campaign in central Gaza will begin Sunday, during a “humanitarian pause” lasting from 6 a.m. until 3 p.m., and another day can be added if needed, said Dr. Rik Peeperkorn, WHO’s representative in the Palestinian territories.

In coordination with Israeli authorities, the effort will then move to southern Gaza and northern Gaza during similar pauses, he said during a news conference by video from Deir al-Balah in central Gaza.

Who will receive the vaccine?

The vaccination campaign targets 640,000 children under 10, according to WHO.

Each child will receive two drops of oral polio vaccine in two rounds, the second to be administered four weeks after the first.

On Thursday, the head of Israel’s association of public health physicians called on the UN to make sure that Israeli hostages held in Gaza are also included in the vaccination campaign.

In a letter to the directors of the WHO and UNICEF, Dr. Hagai Levine noted that two young brothers, Kfir Bibas, 1, and Ariel Bibas, 5, are among the hostages. He also said many of the adult hostages are overdue for booster shots. None of the hostages have been visited by the Red Cross since they were taken on October 7.

Where are the vaccination sites?

The vaccination sites span Gaza, both inside and outside Israeli evacuation zones, from Rafah in the south to the northern reaches of the territory.

The Ramallah-based Health Ministry said Friday that there would be over 400 “fixed” vaccination sites — the most in Khan Younis, where the population density is the highest and there are 239,300 children under 10.

Displaced Palestinians walk past sewage flowing into the streets of southern Gaza’s Khan Younis, July 4, 2024. (AP Photo/Jehad Alshrafi)

Fixed sites include healthcare centers, hospitals, clinics and field hospitals.

Elsewhere in the territory, there will also be around 230 “outreach” sites — community gathering points that are not traditional medical centers — where vaccines will be distributed.

Where are the vaccines now?

Around 1.3 million doses of the vaccine traveled through the Kerem Shalom checkpoint and are currently being held in “cold-chain storage” in a warehouse in Deir al-Balah.

That means the warehouse is able to maintain the correct temperature so the vaccines do not lose their potency.

A worker unloads a shipment of polio vaccines provided with support from UNICEF to the Gaza Strip through Kerem Shalom, at a depot belonging to Gaza’s Hamas-run health ministry on August 25, 2024. (Eyad Baba/AFP)

Another shipment of 400,000 doses is set to be delivered to Gaza soon.

The vaccines will be trucked to distribution sites by a team of over 2,000 medical volunteers, said Ammar Ammar, a spokesperson for UNICEF.

What challenges lie ahead?

Mounting any sort of campaign that requires traversing the Gaza Strip and interacting with its medical system is bound to pose difficulties.

The UN estimates that approximately 65% of the total road network in Gaza has been damaged. Nineteen of the Strip’s 36 hospitals are out of service.

Displaced Palestinian children queue at a food distribution point in Deir el-Balah in the central Gaza Strip on August 8, 2024. (Eyad Baba/AFP)

The north of the territory is cut off from the south, and travel between the two areas has been challenging throughout the war because of Israeli military operations.

Peeperkorn said Friday that WHO cannot do house-to-house vaccinations in Gaza, as they have in other polio campaigns. When asked about the viability of the effort, Peeperkorn said WHO thinks “it is feasible if all the pieces of the puzzle are in place. ”

How many doses do children need and what happens if they miss a dose?

The World Health Organization says children typically need about three to four doses of oral polio vaccine — two drops per dose — to be protected against polio.

If they don’t receive all of the doses, they are vulnerable to infection.

This is a scene in the emergency polio ward at Haynes Memorial Hospital in Boston on Aug. 16, 1955. The critical patients are lined up close together in iron lung respirators so that a team of doctors and nurses can give fast emergency treatment as needed. (AP Photo)

Doctors have previously found that children who are malnourished or who have other illnesses might need more than 10 doses of the oral polio vaccine to be fully protected.

Are there side effects?

Yes, but they are very rare.

Billions of doses of the oral vaccine have been given to children worldwide and it is safe and effective. But in about 1 in 2.7 million doses, the live virus in the vaccine can paralyze the child who receives the drops.

How did this outbreak in Gaza start?

The polio virus that triggered this latest outbreak is a mutated virus from an oral polio vaccine.

The oral polio vaccine contains a weakened live virus and in very rare cases, that virus is shed by those who are vaccinated and can evolve into a new form capable of starting new epidemics.

Times of Israel staff contributed to this report.

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