The Magen David Adom ambulance service says a man in his 30s is seriously wounded in the shooting attack in the West Bank town of Huwara.
A woman in the car, identified as his wife, is also being taken to a hospital for treatment of traumatic shock.
Media reports say the couple’s young children were in the backseat of the car that came under gunfire.
The gunman apparently dropped the gun used in the attack and fled the scene on foot, according to local officials.
The Israel Defense Forces has launched a manhunt for the suspected terrorist.
الاعلام العبري: " 20 طلقة أصابت مركبة المستوطنين في حوارة من مسافة صفر". pic.twitter.com/nn35fsslFl
— وكالة شهاب للأنباء (@ShehabAgency) March 19, 2023